One thing that's unique to 'Uncharted' is something called 'chasing picture,' where Naughty Dog run a section of gameplay and I'm allowed to ad-lib over it. We call it 'panning for gold.'

'Uncharted' is the best job I've ever had. Film, television, whatever - it's without doubt the best. It's changed my life.

In 'Uncharted,' we do the scenes the same way you would do a film or television show. The motion capture - the performance-capture process - is what makes such a difference for this franchise. So I don't approach it any differently. The other actors and I go in and rehearse scenes together, and then we go in the next day and perform.

I choose material instinctually - at the heart of it are characters that I feel are fresh and original, and allow for an opportunity to, I suppose, explore uncharted ground.

The conservative movement today is like that tall ship with its proud captain: strong, accomplished but veering off course into the dangerous and uncharted waters of big government republicanism.

In a world where it is so easy to neglect, deny, corrupt and suppress the truth, the scientist may find his discipline severe. For him, truth is so seldom the sudden light that shows new order and beauty; more often, truth is the uncharted rock that sinks his ship in the dark.

Have the confidence to focus on uncharted territory. Take chances.

Uncharted territory is a good place to be in.

He who studies medicine without books sails an uncharted sea, but he who studies medicine without patients does not go to sea at all.

As an entrepreneur, you are constantly playing in uncharted territory, and sometimes things don't work out. That doesn't mean you failed; it just means you may be off course.

I like to tread uncharted territory and push myself in terms of performance.

In an instant, the law was transformed: from the last passenger on the safe-haven bandwagon to a pioneer into uncharted territory. For the first time in American history, it was not only legal to relinquish a baby; in Nebraska, it was okay to abandon any child of any age for any reason at any time - with the full protection of the law.

The tailor from 'Avatar' actually made my suit for 'Uncharted 3.' And no, it's not a hand-me-down from Sam Worthington. My 11-year-old would fit in Sam Worthington's. I'm 6' 1, 180 pounds.

Comedy to the Senate? Well, there certainly hasn't been a satirist or a political satirist who's done that. So, that really was uncharted territory during the campaign. But I think it's a good thing. Some people thought that it was an odd career arc, but to me it made absolute sense.

There are no signposts in the sky to show a man has passed that way before. There are no channels marked. The flier breaks each second into new uncharted seas.

Travelers are always discoverers, especially those who travel by air. There are no signposts in the sky to show a man has passed that way before. There are no channels marked. The flier breaks each second into new uncharted seas.

I'm always interested in relationships between women. I'm always interested in how women relate to each other, whether it's a family relationship or it's a friend relationship. That's such uncharted territory in cinema.

To study the phenomena of disease without books is to sail an uncharted sea, while to study books without patients is not to go to sea at all.

A guru is like a live road map. If you want to walk uncharted terrain, I think it is sensible to walk with a road map.

No pessimist ever discovered the secret of the stars, or sailed to an uncharted land, or opened a new doorway for the human spirit.